HIV

We have developed a novel next generation pM NNRTI for HIV that does not show CNS toxicity and maintains activity across different mutations.

This work has been featured on Russian TV https://www.youtube.com/watch?app=desktop&v=XI7iahzIVik

Lane T, Makarov V, Nelson JAE, Meeker RB, Sanna G, Riabova O, Kazakova E, Monakhova N, Tsedilin A, Urbina F, Jones T, Suchy A, Ekins S. N-Phenyl-1-(phenylsulfonyl)-1H-1,2,4-triazol-3-amine as a New Class of HIV-1 Non-nucleoside Reverse Transcriptase Inhibitor. J Med Chem. 2023 May 11;66(9):6193-6217. doi: 10.1021/acs.jmedchem.2c02055. Epub 2023 May 2.PMID: 37130343